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PD-L1 / B7-H1 / CD274 Protein
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Programmed death-1 ligand-1 (PD-L1, CD274, B7-H1) has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune responses and peripheral tolerance. PD-L1/B7-H1 is a member of the growing B7 family of immune molecules and this protein contains one V-like and one C-like Ig domain within the extracellular domain, and together with PD-L2, are two ligands for PD1 which belongs to the CD28/CTLA4 family expressed on activated lymphoid cells. By binding to PD1 on activated T-cells and B-cells, PD-L1 may inhibit ongoing T-cell responses by inducing apoptosis and arresting cell-cycle progression. Accordingly, it leads to growth of immunogenic tumor growth by increasing apoptosis of antigen specific T cells and may contribute to immune evasion by cancers. PD-L1 thus is regarded as promising therapeutic target for human autoimmune disease and malignant cancers. |
Product List:
Recombinant Protein
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Name |
Tag |
Size(ug) |
Vendor |
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Human PD-L1/B7-H1/CD274 Protein |
Fc,His, ECD Fc |
50/100 |
Sinobiological |
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Mouse PD-L1/B7-H1/CD274 Protein |
His,His&Fc,ECD Fc |
50/100 |
Sinobiological |
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Rat PD-L1/B7-H1/CD274 Protein |
Non, Human Cells |
50/100 |
Sinobiological |
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CynomolgusPD-L1/B7-H1/CD274 Protein |
Fc,His |
50/100 |
Sinobiological |
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Canine PD-L1/B7-H1/CD274 Protein |
Fc |
50/100 |
Sinobiological |
Mono antibody
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Name |
Reactivity |
Size |
Application |
Vendor |
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PD-L1 / B7-H1 / CD274 Antibody, Rabbit MAb |
Human |
100/200 |
ELISA,IHC-P,IF,IHC-Fr |
Sinobiological |
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PD-L1 / B7-H1 / CD274 Blocking Antibody |
Human |
50/100 |
FCM |
Sinobiological |
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PD-L1 / B7-H1 / CD274 Antibody, Mouse MAb |
Human |
100/200 |
FCM |
Sinobiological |
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PD-L1 / B7-H1 / CD274 Antibody, Rabbit PAb |
Mouse |
50/100 |
ELISA,IHC-P |
Sinobiological |
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PD-L1 / B7-H1 / CD274 Antibody (PE), Rabbit MAb |
Mouse |
100/200 |
FCM |
Sinobiological |
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PD-L1 / B7-H1 / CD274 Antibody, Rabbit PAb, Antigen Affinity Purified |
Human |
50/100 |
FCM,IF,ICC/IF |
Sinobiological |
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PD-L1 / B7-H1 / CD274 Antibody, Rabbit PAb, Antigen Affinity Purified |
Mouse |
50/100 |
FCM |
Sinobiological |
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PD-L1 / B7-H1 / CD274 Antibody, Rabbit PAb, Antigen Affinity Purified |
Cynomolgus |
50/100 |
FCM |
Sinobiological |
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