Related Products

Molecular

Species

Protein

Antibody

Application

cDNA ORF CLONE
Cell Lysate
qPCR
ELISA Kit
ELISA Pair Set

PCSK9/NARC1

Human

10594-H08H
C-His,Active

10594-MM01
Mouse IgG1

ELISA

10594-RP01
Rabbit IgG Pab

ELISA

10594-T24
Rabbit IgG Pab    Antigen Affinity Purified

ELISA,IHC-P

10594-T16
Rabbit IgG Pab     Antigen Affinity Purified

ELISA

10594-RM03
Rabbit IgG

ELISA

10594-H08H1
C-His

/

/

Rat

80005-R08H
C-His

80005-MM03
Mouse IgG1

ELISA

80005-R007
Rabbit IgG

ELISA

80005-MM06
Mouse IgG1

ELISA

80005-RP02
Rabbit IgG Pab     Antigen Affinity Purified

ELISA

80005-MM04
Mouse IgG1

IHC-P

Mouse

50251-M08H
C-His,Active

50251-RP01
Rabbit IgG Pab

ELISA

50251-RP02
Rabbit IgG Pab     Antigen Affinity Purified

ELISA

50251-T26
Rabbit IgG Pab     Antigen Affinity Purified

IHC-P

50251-R214
Rabbit IgG

ELISA

50251-R106
Rabbit IgG

ELISA

Rhesus

11054-K08H
C-His,Active

/

/

Proprotein convertase subtilisin/kexin type 9 (PCSK9), also known as NARC1 (neural apoptosis regulated convertase), which is a newly identified human secretory subtilase belonging to the proteinase K subfamily of the secretory subtilase family. PCSK9 protein is an enzyme which in humans is encoded by the PCSK9 gene with orthologs found across many species. It is expressed in neuroepithelioma, colon carcinoma, hepatic and pancreatic cell lines, and in Schwann cells. PCSK9 protein is highly expressed in the liver and regulates low density lipoprotein receptor (LDLR) protein levels. Inhibition of PCSK9 protein function is currently being explored as a means of lowering cholesterol levels. Thereby, PCSK9 protein is regarded as a new strategy to treat hypercholesterolemia. PCSK9 protein contributes to cholesterol homeostasis and may have a role in the differentiation of cortical neurons.