Related Products

Molecular

Species

Protein

Antibody

Application

cDNA ORF Clone 
Cell Lysate 
qPCR 
ELISA Kit 
ELISA Pair Set 
Immunomagnetic Beads 

B7-2

Human

10699-H03H
C-human IgG1-Fc&His Active

/

/

10699-H08H
C-His&Active

10699-MM06
Mouse IgG1 Mab

FCM

10699-MM02
Mouse IgG1 Mab

ELISA

10699-RP02
Rabbit IgG PAb  Antigen Affinity Purified

ELISA

10699-RP01
Rabbit IgG Pab

ELISA

10699-R118
Rabbit IgG MAb

ELISA

Mouse

50068-M08H
C-His&Active

50068-RP01
Rabbit IgG Pab

ELISA

50068-R003
Rabbit IgG Mab

ELISA

50068-RP02
Rabbit IgG PAb  Antigen Affinity Purified

ELISA,WB,IP

50068-M03H

C-human IgG1-Fc&His Active

/

/

Rat

80025-R08H
C-His&Active

80025-RP02
Rabbit IgG PAb  Antigen Affinity Purified

ELISA

80025-MM04
Mouse IgG2a MAb

ELISA

Cynomolgus

90270-C02H
C-human IgG1-Fc

/

/

90270-C08H

C-His

90270-R021
Rabbit IgG Mab

ELISA

90270-RP01
Rabbit IgG PAb

ELISA

CD86, also known as B-lymphocyte activation antigen B7-2 (referred to as B70), is a member of the cell surface immunoglobulin superfamily. B7-2 exists predominantly as a monomer on cell surfaces and interacts with two co-stimulatory receptors CD28 and cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) expressed on T cells, and thus induces the signal pathways which regulate T cell activation and tolerance, cytokine production, and the generation of CTL. It is indicated that contacts between B and T helper cells mediated by CD86 encourage signals for the proliferation and IgG secretion of normal B cells and B cell lymphomas. Recent study has revealed that CD86 also promotes the generation of a mature APC repertoire and promotes APC function and survival. CD86 has an important role in chronic hemodialysis, allergic pulmonary inflammation, arthritis, and antiviral responses, and thus is regarded as a promising candidate for immune therapy.