Related Products

Molecular

Species

Protein

Antibody

Application

cDNA ORF Clone 
Cell Lysate
qPCR 
Immunomagnetic Beads  

CAIX

Mouse

50660-M08H
C-His&Active

50660-RP01
Rabbit IgG Pab

ELISA

50660-R001
Rabbit IgG Mab

IHC-P

50660-RP02
Rabbit IgG PAb   

Antigen Affinity Purified

ELISA,WB,IHC-P

Canine

70028-D02H
C-human IgG1-Fc  Active

/

/

70028-D08H
C-His&Active

70028-RP01
Rabbit IgG Pab

ELISA

70028-T52
Rabbit IgG PAb   Antigen Affinity Purified

ELISA,WB,IP

Human

10107-H08H
C-His&Active

10107-R003
Rabbit IgG Mab

ELISA,WB,IP

10107-RP02
Rabbit IgG PAb   

Antigen Affinity Purified

ELISA,IHC-P

10107-R036
Rabbit IgG Mab

ELISA,FCM

10107-RP01
Rabbit IgG Pab

ELISA

10107-H02H
C-human IgG1-Fc Active

/

/

Carbonic anhydrases IX (CA IX), also known as membrane antigen MN or CA9, is a member of the carbonic anhydrase (CA) family and may be involved in cell proliferation and cellular transformation. CAs are zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide (H2O + CO2 = H+ + HCO3–) and thus participate in a variety of biological and physical processes. CA IX protein is expressed primarily in carcinoma cells lines, and the expression is cell density dependent and has been shown to be strongly induced by hypoxia, accordingly facilitates adaptation of tumor cells to hypoxic conditions. It is involved in tumorigenesis through many pathways, such as pH regulation and cell adhesion control. CA IX is used as a marker of tumor hypoxia and as a new therapeutic target for many human carcinomas and cancers.