Related Products

Molecular

Species

Protein

Antibody

Application

cDNA ORF Clone 
Cell Lysate 

CD28

Human

11524-HCCH
C-cleavage

/

/

11524-H02H
C-human IgG1-Fc

/

/

Rat

80302-R08H
C-His

80302-T16
Rabbit IgG PAb  Antigen Affinity Purified

ELISA

80302-R02H
C-human IgG1-Fc

/

/

Mouse

50103-M08H
C-His

50103-RP02
Rabbit IgG PAb  

Antigen Affinity Purified

ELISA,IHC-P

50103-RP01
Rabbit IgG Pab

ELISA

50103-T48
Rabbit IgG PAb    Antigen Affinity Purified

ELISA,WB

50103-M03H
C-human IgG1-Fc&His Active

/

/

Cynomolgus

90182-C02H
C-His

/

/

The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 19 (CD19) is a member of CD system. CD19 is a cell surface molecule that assembles with the antigen receptor of B-cells. This results in a descent in threshold for antigen receptor-dependent stimulation. A simplified view holds that the ability of B-cells to respond to the various antigens in a specific and sensitive manner is achieved in the presence of low-affinity antigen receptors. CD19 primarily acts as a B-cell coreceptor in conjunction with CD21 and CD81. The formation of the receptor complex is induced by antigen and CD19, induced by exogenous antigen, has been found cytoplasmic tail phosphorylated and bind to sIg.