Related Products

Molecular

Species

Protein

Antibody

Application

cDNA ORF Clone
Cell Lysate 
qPCR
ELISA Pair Set
ELISA Kit

CD62E/SELE

Human

10335-H08H
C-His,Active

10335-MM10-F
Mouse IgG2b Mab(FITC)

 FCM

10335-MM10-P
Mouse IgG2b Mab

 FCM

10335-MM03
Mouse IgG1 Mab 

ELISA

10335-MM04
Rabbit IgG Mab

FCM

10335-MM10
Mouse IgG2b Mab

ELISA

10335-MM10-A
Mouse IgG2b Mab (APC)

ELISA

10335-R103-F
Rabbit IgG Mab(FITC)

 FCM

10335-R103-P
Rabbit IgG Mab(PE)

 FCM

10335-RP01
Rabbit IgG Pab

ELISA

10335-R208
Rabbit IgG Mab

IF,ICC/IF

10335-R040
Rabbit IgG Mab

ELISA,WB

10335-RP02
Rabbit IgG PAb, Antigen Affinity Purified

 FCM

10335-R103
Rabbit IgG Mab

ELISA,FCM

10335-H03H
C-human IgG1-Fc&His Active

/

/

Cynomolgus

90169-C08H
C-His

90169-MM03
Mouse IgG1 Mab   

ELISA

90169-RP01
 Rabbit IgG Pab

ELISA

90169-R105
Rabbit IgG Mab

ELISA

90169-T16
Rabbit IgG PAb, Antigen Affinity Purified

ELISA

90169-C02H
C-human IgG1-Fc

/

/

Rat

80033-R02H
C-human IgG1-Fc

/

/

80033-R08H
C-His,Active

80033-RP02
Rabbit IgG Pab, Antigen Affinity Purified

ELISA

80033-R046
Rabbit IgG Mab

ELISA

80033-T16
Rabbit IgG Pab, Antigen Affinity Purified

ELISA

80033-RP01
Rabbit IgG Pab

ELISA

80033-MM04
Mouse IgG1 Mab

ELISA

80033-R102
Rabbit IgG Mab

ELISA

80033-MM01
 Mouse IgG1 Mab

ELISA

Mouse

50736-M02H
C-human IgG1-Fc

/

/

50736-M08H
C-His,Active

50736-T16
Rabbit IgG Pab, Antigen Affinity Purified 

ELISA

50736-RP01
Rabbit IgG Pab

ELISA

50736-MCCH
C-cleavage

/

/

E-selectin, also known as endothelial leukocyte adhesion molecule-1 (ELAM-1) and CD62E, is an inducible adhesion molecule that is expressed on the surfaces of stimulated vascular endothelial cells and is sometimes involved in cancer cell metastasis. E-selectin exhibits a complex mosaic structure consisting of a large extracellular region comprised of a lectin domain, an EGF-like domain, and a short consensus repeat (SCR) domain, followed by a transmembrane region and a relatively short (32 aa) cytoplasmic tail. As a member of the LEC-CAM or selectin family, E-selectin recognises and binds to sialylated carbohydrates including members of the Lewis X and Lewis A families found on monocytes, granulocytes, and T-lymphocytes. E-selectin supports rolling and stable arrest of leukocytes on activated vascular endothelium, and furthermore, it was indicated that it can also transduce an activating stimulus via the MAPK cascade into the endothelial cell during leukocyte adhesion. E-selectin regulates adhesive interactions between certain blood cells and endothelium. The soluble form of E selectin (sE-selectin) is a marker of endothelial activation, and has a potential role in the pathogenesis of cardiovascular disease as raised levels have been found in hypertension, diabetes and hyperlipidemia, although its association in established atherosclerosis disease and its value as a prognostic factor is more controversial. soluble E-selectin is inversely associated with the muscular component of the left ventricle, thereby suggesting that the lack of such a reparative factor may be associated with cardiac remodeling in end-stage renal disease (ESRD) patients. In addition, this adhesion molecule appears to be involved in the pathogenesis of atherosclerosis.