Related Products

Molecular

Species

Protein

Antibody

Application

cDNA ORF Clone 
Cell Lysate 
qPCR 
ELISA Pair Set 

CEACAM1

Human

10822-H08H
C-His&Active

10822-R103
Rabbit IgG MAb

FCM,IF,ICC/IF

10822-RP01
Rabbit IgG PAb

ELISA,WB

10822-RP04
Rabbit IgG PAb,Antigen Affinity Purified

ELISA,WB

10822-MM02
Mouse IgG1 Mab

ELISA,IHC-P,FCM

10822-MM02-A
Mouse IgG1 MAb

FCM

10822-H03H
C-human IgG1-Fc&His

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Rat

80224-R08H
C-His

80224-MM03-P
Mouse IgG1 Mab

FCM

80224-RP01
Rabbit IgG Pab

ELISA

80224-T16
Rabbit IgG PAb,Antigen Affinity Purified

ELISA,IHC-P

Mouse

50571-M08H
C-His

50571-RP01
Rabbit IgG Pab

ELISA

50571-RP02
Rabbit IgG PAb,Antigen Affinity Purified

ELISA,IHC-P

50571-R030
Rabbit IgG Mab

IHC-P

50571-M02H
C-human IgG1-Fc

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The carcinoembryonic-antigen-related cell-adhesion molecule (CEACAM) family of proteins has been implicated in various intercellular-adhesion and intracellular-signalling-mediated effects that govern the growth and differentiation of normal and cancerous cells. CEACAM1, also known as biliary glycoprotein I (BGP I) and CD66a, is a member of the carcinoembryonic antigen (CEA) gene family which belongs to the immunoglobulin superfamily. The highly glycosylated CEACAM1 contains one N-terminal V-type Ig-like domain and three C2-type Ig-like domains within its ECD, and one ITIM motif and a calmodulin binding site in the cytoplasmic region. CEACAM1 is a surface glycoprotein expressed on various blood cells, epithelial cells, and vascular cells. It was described as an adhesion molecule mediating cell adhesion via both homophilic and heterophilic manners, and was detected on leukocytes, epithelia, and endothelia. Studies have revealed that CEACAM1 performs actions in multiple cellular processes including tissue differentiation, angiogenesis, apoptosis, metastasis, as well as the modulation of innate and adaptive immune responses.