Related Products

Molecular

Species

Protein

Antibody

Application

cDNA ORF Clone  
Cell Lysate  
qPCR
Immunomagnetic Beads

Flt3

Mouse

51119-M08H
C-His

/

/

51113-M02H
C-human IgG1-Fc

/

/

Human

10315-H07B
N-His

10315-RP01
Rabbit IgG Pab

ELISA

10315-T16
Rabbit IgG Pab,Antigen Affinity Purified

ELISA

10445-H08H
C-His

10445-MM02
Mouse IgG1 Mab

FCM

10445-RP02
Rabbit IgG Pab,Antigen Affinity Purified

ELISA,WB,IP

10445-MM02-A
Mouse IgG1 Mab(APC)

FCM

10445-MM05
Mouse IgG1 Mab

ELISA

10445-MM02-F
Mouse IgG1 Mab(FITC)

FCM

Human epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein, and belongs to the epidermal growth factor (EGF) receptor family. HER2 protein cannot bind growth factors due to the lacking of ligand binding domain of its own and autoinhibited constitutively. However, HER2 forms a heterodimer with other ligand-bound EGF receptor family members, therefore stabilizes ligand binding and enhances kinase-mediated activation of downstream molecules. HER2 plays a key role in development, cell proliferation and differentiation. HER2 gene has been reported to associate with malignancy and a poor prognosis in numerous carcinomas, including breast, prostate, ovarian, lung cancers and so on.