Related Products

Molecular

Species

Protein

Antibody

Application

cDNA ORF Clone
qPCR
Cell Lysate

IL13RA2

Human

10350-H03H
C-human IgG1-Fc& His,Active

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10350-H08H
C-His,Active

10350-T16
Rabbit IgG Pab,Antigen Affinity Purified

ELISA

10350-RP01
Rabbit IgG Pab

ELISA

Mouse

50061-M08H
C-His,Active

50061-R015
 Rabbit IgG Mab

ELISA

50061-RP01
Rabbit IgG Pab

ELISA

50061-RP02
Rabbit IgG Pab,Antigen Affinity Purified

ELISA

50061-M03H
C-human IgG1-Fc& His,Active

/

/

Canine

70079-D02H
C-human IgG1-Fc

/

/

70079-D08H
C-His

/

/

Rat

80204-R08H
C-His

80204-R007
Rabbit IgG Mab

ELISA

80204-RP01
Rabbit IgG Pab

ELISA

80204-RP02
Rabbit IgG Pab,Antigen Affinity Purified

ELISA,IHC-P

80204-R02H
C-human IgG1-Fc

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Interleukin-13 receptor subunit alpha-2 (IL13RA2/IL-13RA2) is also known as also known as cluster of differentiation 213A2 (CD213A2), IL-13 receptor subunit alpha-2, IL-13R subunit alpha-2, and IL-13RA2. The IL13RA2 is often overexpressed in brain tumors, making Il13ra2 one of the vaccine targets for immunotherapy of glioma. IL13RA2/IL-13RA2 is a cancer-associated receptor that is present in greater than 80% of High Grade Astrocytomas (HGA) and has recently been recognized as a cytokine that predisposes breast cancer cells to metastasize. Expression of IL13Rα2 was rapidly lost from the surface of transduced cells grown in culture. The loss appeared to be related to ligands present in fetal bovine serum in the medium. None of the malignant glioma cell lines cultivated in vitro and tested to date exhibited the IL13Rα2 receptor. A recombinant virus (R5111) enters cells via its interaction with the IL13Rα2 receptor in a manner that cannot be differentiated from the interaction of wild-type virus with its receptors.