Related Products

Molecular

Species

Protein

Antibody

Application

cDNA ORF Clone 
qPCR 
Cell Lysate  
ELISA Kit  

IL4R

Mouse

51180-M08H
C-His

51180-T16
Rabbit IgG Pab,Antigen Affinity Purified

ELISA

51180-R074
Rabbit IgG Mab

ELISA

Canine

80198-R02H
C-human IgG1-Fc&Active

/

/

80198-R08H
C-His

80198-T16
Rabbit IgG Pab,Antigen Affinity Purified

ELISA

80198-R002
Rabbit IgG Mab

ELISA

80198-RP01
Rabbit IgG Pab

ELISA

Human

10402-H08H
C-His&Active

10402-MM01
Mouse IgG1 Mab

ELISA

10402-R401
Rabbit IgG Neutralizing Antibody

B/N

10402-RP02
Rabbit IgG Pab,Antigen Affinity Purified

ELISA

10402-R102
Rabbit IgG Mab

ELISA

10402-RP01
Rabbit IgG Pab

ELISA

10402-R209
Rabbit IgG Mab

FCM

The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD124, also known as interleukin 4 receptor (IL4R), is a typeⅠ transmembrane protein that can regulate IgE antibody production in B cells through binding to interleukin 4 and interleukin 13 and promote differentiation of Th2 cells through binding to interleukin 4. The membrane-bound form of CD124 can be hydrolyzed to soluble form which can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells.