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Related Products |
Molecular |
Species |
Protein |
Antibody |
Application |
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cDNA ORF Clone Cell Lysate qPCR ELISA Pair Set Immunomagnetic Beads |
RBP4 |
Mouse |
50170-M08H C-His&Active |
50170-RP01 Rabbit IgG Pab |
ELISA |
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50170-R008-F Rabbit IgG Mab |
FCM |
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50170-R025 Rabbit IgG Mab |
ELISA |
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50170-R008 Rabbit IgG Mab |
FCM,IF,ICC/IF |
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50170-RP02 Rabbit IgG Pab,Antigen Affinity Purified |
ELISA,WB |
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50170-R001 Rabbit IgG Mab |
ELISA,WB |
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Canine |
70006-D08H C-His&Active |
70006-T48 Rabbit IgG Pab,Antigen Affinity Purified |
ELISA,WB |
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70006-D02H C-human IgG1-Fc&Active |
50500-R202 Rabbit IgG Mab |
ELISA |
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Human |
10354-H08H C-His&Active |
10354-MM15-P Mouse IgG1 Mab |
FCM |
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10354-MM01 Mouse IgG1 Mab |
ELISA |
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10354-MM15 Mouse IgG1 Mab |
ELISA,IHC-P |
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10354-MM11 Mouse IgG1 Mab |
ELISA,IHC-P |
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10354-MM06 Mouse IgG1 Mab |
FCM |
|
10354-RP01 Rabbit IgG Pab |
ELISA |
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10354-MM15-F Mouse IgG1 Mab(FITC) |
FCM |
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10354-RP02 Rabbit IgG Pab,Antigen Affinity Purified |
ELISA,WB,IHC-P,IP |
|
Rat |
80008-R08H C-His&Active |
80008-RP02 Rabbit IgG Pab,Antigen Affinity Purified |
ELISA,WB,IHC-P |
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80008-RP01 Rabbit IgG Pab |
ELISA |
|
Cynomolgus |
90220-C08H C-His |
90220-T60 Rabbit IgG Pab,Antigen Affinity Purified |
ELISA,WB,IHC-P,IP |
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Retinol-binding protein 4 (RBP4) is the specific carrier for retinol (also known as vitamin A), and is responsible for the conversion of unstable and insoluble retinol in aqueous solution into stable and soluble complex in plasma through their tight interaction. As a member of the lipocalin superfamily, RBP4 containing a β-barrel structure with a well-defined cavity is secreted from the liver, and in turn delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP4-retinol complex interacts with transthyretin (TTR), and this binding is crucial for preventing RBP4 excretion through the kidney glomeruli. RBP4 expressed from an ectopic source efficiently delivers retinol to the eyes, and its deficiency affects night vision largely. Recently, RBP4 as an adipokine, is found to be expressed in adipose tissue and correlated with obesity, insulin resistance (IR) and type 2 diabetes (T2DM). |
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