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Spike (sino biological Inc.)
 

Related Products

Molecular

Species

Protein

Antibody

Application

cDNA ORF Clone  
Cell Lysate  
qPCR
Immunomagnetic Beads

Spike

MERS-CoV

40070-V08B
C-His

40070-T60
Rabbit IgG Pab,Antigen Affinity Purified

ELISA,WB,IHC-P,IP

40070-MM11
Mouse IgG1 Mab

ELISA,WB,IF,IP

40069-V08B
C-His&Active

40069-RP02
Rabbit IgG Pab,Antigen Affinity Purified

ELISA,WB,IHC-P,FCM,IHC,IF,IP,ICC/IF

40069-T52
Rabbit IgG Pab,Antigen Affinity Purified

ELISA,WB,IP

40069-R723
Rabbit IgG Mab

MN

40069-MM23
Mouse IgG1 Mab

ELISA,FCM,IF,ICC/IF

40069-T44
Rabbit IgG Pab,Antigen Affinity Purified

WB,IHC-P,IP

40069-RP01
Rabbit IgG Pab

ELISA,FCM,IF,IP,ICC/IF

40069-V08B1
C-His&Active

40069-T48
Rabbit IgG Pab,Antigen Affinity Purified

ELISA,WB

40071-V05B
C-rabbit IgG-Fc&Active

/

/

40071-V08B1
C-His

/

/

40071-V31B
C-rabbit IgG-Fc&Active

/

/

40069-V08H
C-His&Active

/

/

Ebola virus

40442-V08H4
C-His&Active

/

/

Human

40150-V08B1
C-His

40150-T60
Rabbit IgG Pab,Antigen Affinity Purified

ELISA,WB,IHC-P,IP

40150-RP01
Rabbit IgG Pab

ELISA,IHC-P,FCM,IF,IP,ICC/IF

40150-MM02
Mouse IgG1 Mab

ELISA,FCM,IF,ICC/IF

13659-H07E
N-His

13659-RP01
Rabbit IgG Pab

ELISA

13659-T16
Rabbit IgG Pab,Antigen Affinity Purified

ELISA

40150-V08B2
C-His

40150-T52
Rabbit IgG PAb,Antigen Affinity Purified

ELISA,WB,FCM,IP

40150-V31B2
C-rabbit IgG-Fc

/

/

40021-V08H
C-His&Active

40021-MM07
Mouse IgG1 Mab

ELISA,FCM,IF,ICC/IF

40021-R028
Rabbit IgG Mab

ELISA,IHC-P,FCM,IF,ICC/IF

40021-RP01
Rabbit IgG Pab

ELISA,IHC-P,FCM,IF,IP,ICC/IF

40021-T60
Rabbit IgG PAb,Antigen Affinity Purified

ELISA,WB,IHC-P,IP

40071-V31B1
C-rabbit IgG-Fc

/

/

The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell: they are essential for both host specificity and viral infectivity. The term 'peplomer' is typically used to refer to a grouping of heterologous proteins on the virus surface that function together. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. The SARS-CoV spike (S) protein is composed of two subunits; the S1 subunit contains a receptor-binding domain that engages with the host cell receptor angiotensin-converting enzyme 2 and the S2 subunit mediates fusion between the viral and host cell membranes. The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity, during infection with SARS-CoV.

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