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Related Products |
Molecular |
Species |
Protein |
Antibody |
Application |
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cDNA ORF Clone Cell Lysate qPCR Immunomagnetic Beads |
Spike |
MERS-CoV |
40070-V08B C-His |
40070-T60 Rabbit IgG Pab,Antigen Affinity Purified |
ELISA,WB,IHC-P,IP |
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40070-MM11 Mouse IgG1 Mab |
ELISA,WB,IF,IP |
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40069-V08B C-His&Active |
40069-RP02 Rabbit IgG Pab,Antigen Affinity Purified |
ELISA,WB,IHC-P,FCM,IHC,IF,IP,ICC/IF |
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40069-T52 Rabbit IgG Pab,Antigen Affinity Purified |
ELISA,WB,IP |
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40069-R723 Rabbit IgG Mab |
MN |
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40069-MM23 Mouse IgG1 Mab |
ELISA,FCM,IF,ICC/IF |
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40069-T44 Rabbit IgG Pab,Antigen Affinity Purified |
WB,IHC-P,IP |
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40069-RP01 Rabbit IgG Pab |
ELISA,FCM,IF,IP,ICC/IF |
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40069-V08B1 C-His&Active |
40069-T48 Rabbit IgG Pab,Antigen Affinity Purified |
ELISA,WB |
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40071-V05B C-rabbit IgG-Fc&Active |
/ |
/ |
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40071-V08B1 C-His |
/ |
/ |
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40071-V31B C-rabbit IgG-Fc&Active |
/ |
/ |
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40069-V08H C-His&Active |
/ |
/ |
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Ebola virus |
40442-V08H4 C-His&Active |
/ |
/ |
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Human |
40150-V08B1 C-His |
40150-T60 Rabbit IgG Pab,Antigen Affinity Purified |
ELISA,WB,IHC-P,IP |
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40150-RP01 Rabbit IgG Pab |
ELISA,IHC-P,FCM,IF,IP,ICC/IF |
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40150-MM02 Mouse IgG1 Mab |
ELISA,FCM,IF,ICC/IF |
|
13659-H07E N-His |
13659-RP01 Rabbit IgG Pab |
ELISA |
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13659-T16 Rabbit IgG Pab,Antigen Affinity Purified |
ELISA |
|
40150-V08B2 C-His |
40150-T52 Rabbit IgG PAb,Antigen Affinity Purified |
ELISA,WB,FCM,IP |
|
40150-V31B2 C-rabbit IgG-Fc |
/ |
/ |
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40021-V08H C-His&Active |
40021-MM07 Mouse IgG1 Mab |
ELISA,FCM,IF,ICC/IF |
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40021-R028 Rabbit IgG Mab |
ELISA,IHC-P,FCM,IF,ICC/IF |
|
40021-RP01 Rabbit IgG Pab |
ELISA,IHC-P,FCM,IF,IP,ICC/IF |
|
40021-T60 Rabbit IgG PAb,Antigen Affinity Purified |
ELISA,WB,IHC-P,IP |
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40071-V31B1 C-rabbit IgG-Fc |
/ |
/ |
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The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell: they are essential for both host specificity and viral infectivity. The term 'peplomer' is typically used to refer to a grouping of heterologous proteins on the virus surface that function together. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. The SARS-CoV spike (S) protein is composed of two subunits; the S1 subunit contains a receptor-binding domain that engages with the host cell receptor angiotensin-converting enzyme 2 and the S2 subunit mediates fusion between the viral and host cell membranes. The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity, during infection with SARS-CoV. |
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